Herpes sub unit vaccine

Details Herpes sub unit vaccine Herpes sub unit vaccine

1980-02-11

1983-02-15

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Lymphokine

435235, A61K 39245

Patent

active

043741274

ABSTRACT:
Herpes virus subunit antigens suitable for vaccine use are prepared by (1) treating virus-infected cells with a surfactant and varying concentrations of salt to extract and solubilize viral-directed glycoproteins, (2) fractionating the solubilized material by chromatographic procedures to enrich the viral-directed glycoproteins and to remove unwanted proteins and nucleic acids, and (3) optionally treating the subunit antigens with deoxyribonuclease and formaldehyde to assure safety.

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