Herpes simplex virus strains

Details Herpes simplex virus strains Herpes simplex virus strains

2006-07-18

2006-07-18

Epps-Ford, Janet L. (Department: 1633)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

C435S320100, C435S325000, C435S091410, C435S091420, C435S455000

Reexamination Certificate

active

07078029

ABSTRACT:
The present invention provides an HSV having a genome with a mutation of a TAATGARAT sequence such that, in the presence of a ICP4 gene product, a native immediate early gene is expressed from the genome with delayed kinetics, the genome having a further inactivating mutation of each of the genes encoding ICP4.

REFERENCES:
patent: 5026635 (1991-06-01), Ferguson et al.
patent: 5070010 (1991-12-01), Hsu
patent: 5124263 (1992-06-01), Temin et al.
patent: 5658724 (1997-08-01), DeLuca
patent: 5672344 (1997-09-01), Kelley et al.
patent: 5674722 (1997-10-01), Mulligan et al.
patent: 5804413 (1998-09-01), DeLuca
patent: 0 453 242 (1991-10-01), None
patent: WO 95/13391 (1995-05-01), None
patent: WO 96/24663 (1996-08-01), None
Mackem et al., Journal of Virology, 44:939-949 (1982).
Misra V et al., Journal of Virology, 68:4898-4909 (1994).
Pizer Li et al., Nucleic Acids Research, 19:477-483 (1991).
Post Le et al., Cell 25:227-232 (1981).
Resnick J et al., ournal of Virology 63:2497-2503 (1989).
Batchelor et al.,Journal of Virology, 64(7), 3269-3279 (1990).
Breakefield et al.,The New Biologist, 3(3), 203-218 (1991).
Breakefield et al.,Treatment of Genetic Diseases, (Desnick ed.), 287-319 (1991).
Chiocca et al.,The New Biologist, 2(8), 739-746 (1990).
Croen et al.,New England Journal of Medicine, 317(23), 1427-1432 (1987).
DeLuca et al.,Journal of Virology, 56(2), 558-570 (1985).
DeLuca et al.,Nucleic Acids Research, 15(11), 4491-4511 (1987).
DeLuca et al.,Journal of Virology, 62(3), 732-743 (1988).
Dobson et al.,Journal of Virology, 63(9), 3844-3851 (1989).
Dobson et al.,Neuron, 5(3), 353-360 (1990).
Douville et al.,Virology, 207(1), 107-116 (1995).
Glorioso et al.,Seminars in Virology, 3(4), 265-276 (1992).
Goins et al.,Journal of Virology, 68(4), 2239-2252 (1994).
Ho et al.,Proceedings of the National Academy of Sciences of the United States of America, 86(19), 7596-7600 (1989).
Imbalzano et al.,Journal of Virology, 65(2), 565-574 (1991).
Johnson et al.,Journal of Virology, 65(5), 2952-2965 (1992).
Johnson et al.,Journal of Virology, 68(10), 6347-6362 (1994).
Kmetz et al.,Nucleic Acids Research, 16(10), 4735 (1988).
Krisky et al.,Gene Therapy, 5, 1593-1603 (1998).
Lokensgard et al.,Journal of Virology, 68(11), 7148-7158 (1994).
McCarthy et al. ,Journal of Virology, 63(1), 18-27 (1989).
Ngo et al.,The Protein Folding Problem and Tertiary Structure Prediction, (Merz et al. eds.), 434-506 (1994).
Orkin et al.,Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy, 1-39 (1995).
Paterson et al.,Nucleic Acids Research, 16(23), 11005-11025 (1988).
Paterson et al.,Virology, 166(1), 186-196 (1988).
Post et al.,Cell, 25, 227-232 (1981).
Rivera-Gonzalez et al.,Virology, 202(2), 550-564 (1994).
Roizman et al.,Virology, (Fields ed.), 497-526 (1985).
Sacks et al.,Journal of Virology, 55(3), 796-805 (1985).
Sacks et al.,Journal of Virology, 61(3), 829-839 (1987).
Samaniego et al.,Journal of Virology, 69(9), 5705-5715 (1995).
Samaniego et al.,Journal of Virology, 71(6), 4614-4625 (1997).
Samaniego et al.,Journal of Virology, 72(4), 3307-3320 (1998).
Sears et al.,Journal of Virology, 55(2), 338-346 (1985).
Shepard et al.,Journal of Virology, 65(2), 787-795 (1991).
Shih et al.,Proceedings of the National Academy of Sciences of the United States of America, 81(18), 5867-5870 (1984).
Spector et al.,Journal of Virology, 3504-3513 (1991).
Walker et al.,Cell, 79(5), 841-852 (1994).
Werstuck et al.,Journal of Virology, 64(3), 984-991 (1990).
Wu et al.,Journal of Virology, 70(9), 6358-6369 (1996).
Shepard et al., “Separation of Primary Structural Components Conferring Autoregulation, Transactivation, and DNA-Binding Properties to the Herpes Simplex Virus Transcriptional Regulatory Protein ICP4,”Journal of Virology, 63(9): 3714-3728 (Sep. 1989).
Bandyopadhyay et al., “Expression from an Internal AUG Codon of Herpes Simplex Thymidine Kinase Gene Inserted in a Retrovirus Vector,”Molecular and Cellular Biology, 4(4): 743-748 (Apr. 1984).
Shepard et al., “Separation of Primary Structural Components Conferring Autoregulation, Transactivation, and DNA-Binding Properties to the Herpes Simplex Virus Transcriptional Regulatory Protein ICP4,”Journal of Virology,63(9): 3714-3728 (Sep. 1989).
Bandyopadhyay et al., “Expression from an Internal AUG Codon of Herpes Simplex Thymidine Kinase Gene Inserted in a Retrovirus Vector,”Molecular and Cellular Biology,4(4): 743-748 (Apr. 1984).

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