Herpes simplex virus amplicon mini-vector gene transfer system

Details Herpes simplex virus amplicon mini-vector gene transfer system Herpes simplex virus amplicon mini-vector gene transfer system

1995-12-26

1998-11-03

Duzo, David

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

4353201, 435364, C12N 15389, C12N 510, C12N 1586

Patent

active

058307273

ABSTRACT:
A novel HSV mini viral vector is disclosed. The vector comprises HSV and EBV genes which allow it to remain in episomal state, to have very high transfection and infection, and to tolerate up to 140 kb of foreign DNA. Techniques and genetic constructs for producing the vectors, for constructing the vectors and transfection and infection to recipient cells are disclosed.

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