Herbicidal method

Plant protecting and regulating compositions – Plant growth regulating compositions – Organic active compound containing

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A01N 4380

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active

061567019

DESCRIPTION:

BRIEF SUMMARY
FIELD OF THE INVENTION

The present invention is directed to the use of 3-ester-4-benzoylisoxazoles as a selective pre-emergence and post-emergence herbicide in corn.


BACKGROUND OF THE INVENTION

The protection of crops from weeds and other vegetation which inhibit crop growth is a constantly recurring problem in agriculture. To help combat this problem researchers in the field of synthetic chemistry have produced an extensive variety of chemicals and chemical formulations effective in the control of such unwanted growth. Chemical herbicides of many types have been disclosed in the literature and a large number are in commercial use.
Unfortunately, many of such herbicides will exhibit phototoxicity to the desired crop as well as to the weeds sought to be controlled. Thus, there is a long-standing need for selective herbicides which will not adversely affect the crop plants when applied at herbicidally effective levels.
Isoxaflutole [5-cyclopropyl-4-(2-methylsulfonyl-4-trifluoromethyl)benzoylisoxazole] is disclosed in European Patent Publication No. EP-0527036 and is a highly effective herbicide in corn. used pre-emergence or pre-plant incorporated [see for example Vrabel et al., Proc. North Cent. Weed Sci. Soc. Volume 49. pages 49-50 (1994); and Luscombe et al. Proc. Br. Crop Prot. Conf. Weeds. Volume 1. pages 35-42 (1995)]. At elevated dose rates however, or when applied post-emergence a problem can exist that corn may be damaged by this compound. European Patent Publication No. EP-0487357 describes. interalia. 3-ester-4-benzoylisoxazoles having activity against a variety of weed species. In particular, EP-0487357 describes ethyl 5-cyclopropyl-4-(2-methylsulfonyl-4-trifluoromethyl)benzoylisoxazole-3-car boxylate (as Compound BB).
It has now been discovered that such compounds will effectively control a broad range of weeds typically associated with corn without exhibiting any substantial phytotoxic effects on the corn itself.


DESCRIPTION OF THE INVENTION

This invention is directed to a method of selectively controlling undesirable vegetation in corn, comprising application of an herbicidally effective amount of an isoxazole having the formula (I): ##STR2##
wherein R is a straight- or branched-C.sub.1-6 alkyl, to the locus of such vegetation.
As is employed herein, the term "herbicide" is used to denote a compound which controls or modifies the growth of plants. The term "herbicidally effective amount" is used to indicate the quantity of such compound which is capable of producing a controlling or modifying effect. Controlling or modifying effects include all deviations from natural development, for example: killing, retardation, leaf burn, albinism, dwarfing, and the like. The term "plants" refers to all physical parts of a plant including seeds, seedlings, saplings, roots, tubers, stems, stalks, foliage and fruits. Preferably R is straight- or branched C.sub.1-3 alkyl. Most preferably R is ethyl, i.e. ethyl 5-cyclopropyl-4-(2-methylsulfonyl-4-trifluoromethyl)benzoylisoxazole-3-car boxylate, which is hereafter referred to as Compound A. Compounds of formula (I) above are known from EP-0487357 or can be prepared by the methods described in that publication.
In the practice of the present invention isoxazole is applied to the locus of the vegetation to be controlled. Application rates will depend on the particular plant species and degree of control desired. In general, application rates of from about 10 to about 250 g/ha may be employed, with rates of from about 50 to about 200 g/ha being preferred, and from about 50 to about 150 g/ha more preferred, about 75 to about 150 g/ha even more preferred.
The compound of formula (I) can be formulated in the same manner in which herbicides are generally formulated. The object of the formulation is to apply the compositions to the locus where control is desired by a convenient method. The "locus" is intended to include soil, as well as established vegetation.
The method can be used by pre- or post-emergence application.
By the term `pre-emergence application` i

REFERENCES:
patent: 5656573 (1997-08-01), Roberts et al.
patent: 5837652 (1998-11-01), Anderson-Taylor et al.
Luscombe et al., Proc. Br. Crop. Prot. Conf. Weeds, vol. 1, pp. 35-42 (1995).
CAB International, CAB Accession No. 972303038 (1997), abstract of Bhowmik et al, Proceedings of the Second International Weed Control Congress, Copenhagen, Denmark, Jun. 25-28, 1996, vol. 1-4, pp. 807-812. (Abstract Only).

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