Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Reexamination Certificate
1999-03-18
2001-03-06
Lilling, Herbert J. (Department: 1651)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
Reexamination Certificate
active
06197306
ABSTRACT:
This invention relates to a herbal composition for the treatment of chronic obstructive pulmonary disease, bronchitis and respiratory disorders and the process of preparing the same.
BACKGROUND
Excess smoking irritates the bronchial tube and lowers their resistance so that they become vulnerable. It leads to a condition called bronchitis. The inflammation of the mucus membrane lining the bronchiole and bronchial tube within the chest with breathing disorder affecting the expiratory function is the characteristic feature.
In most cases of bronchitis, the larynx, trachea and bronchia tubes are acutely inflamed. The tissues are swollen due to irritation. Large quantities of mucus are secreted and poured into the windpipe to protect the inflamed mucus membrane. The phlegm, when expelled is found to be viscid and purulent. There is usually a high fever, some difficulty in breathing and deep chest cough. Other symptoms are hoarseness and pain in the chest and loss of appetite. Breathing trouble continuous till the inflammation subsides and mucus is removed.
Chronic Obstructive Pulmonary Disease (COPD) features progressive chronic airflow obstruction due to chronic bronchitis, emphysema or both. The obstruction of airflow may be partly reversible and some patients may manifest bronchial hyper-responsiveness.
There are several Indian traditional medicines recommended for treatment. For instance Cofdry, Kolet and Zecuf The composition of these medicines are given below:
Cofdry
Koflet
Zecuf
(10 ml
(5 ml
(10 ml
contains)
contains)
contains)
Curcuma longu
—
50 mg
—
Tulsi
200 mg
100 mg
100 mg
Yasthimadhu
50 mg
100 mg
60 mg
Haridra
—
—
50 mg
Shunthi
—
—
10 mg
Vasaka
200 mg
200 mg
60 mg
Brahati
—
—
20 mg
Push kammool
—
—
20 mg
Sugdha muricha
—
—
10 mg
Vibhitaka
—
50 mg
—
Viola odorata
—
—
20 mg
Grita Kunari and
—
—
6 mg
Pepermint salt
Ocimum santum
200 mg
—
—
Zingiber offiundi
—
25 mg
—
Solanum xantho carpum
100 mg
—
—
S. Irilobatum
50 mg
—
—
Glycynhiya glabra
50 mg
—
—
Alpinia chinensis
50 mg
—
—
Cinnanomum zylanica
25 mg
—
—
C. tanda
25 mg
—
—
Piper longum
25 mg
20 mg
—
Myristica fragrans
25 mg
—
—
Cubeba officinalis
25 mg
—
—
Cinnamomum canphora
10 mg
—
—
Termindig bellerica
—
200 mg
—
Pudina phool
—
—
—
Mentha arvensi
—
3 mg
—
Eucalyphis Oil
—
2 mg
—
Syrup
—
—
—
Navsagar (NH
4
Cl
2
)
—
30 mg
—
The above medicines are not effective against chronic obstructive pulmonary disease, bronchitis and respiratory disorder.
The object of this invention is to provide a simple but effective composition for treatment of chronic obstructive pulmonary disease, bronchitis and respiratory disorder.
To achieve the said objective this invention provides a process of preparing a herbal composition for the treatment of Chronic Obstructive Pulmonary Disease (COPD), bronchitis and respiratory disorders comprising:
washing and cleaning the plant materials of Bryocnia, Ipecacuanha and Drosera,
surface sterilizing the said plant materials with sodium hypochlorite and drying,
cutting the dried plant materials into small pieces individually,
grinding and pulverizing the said plant materials separately, preferably of 1 mm particle size,
extracting the said granulated plant materials separately in a polar solvent and evaporating the said solvent under vacuum to get the extracted materials in powder form,
mixing at least two of the said extracted materials with the antimony potassium tartarate in the ratio 100-75:0-25 to prepare said desired herbal composition.
The solvent used are ketones, alcohols, esters, ethers, nitryles, amides, sulfoxides, substituted aliphatic hydrocarbons, aromatic hydrocarbons and substituted aromatic hydrocarbons and mixtures thereof preferrably acetone, benzene, dichloromethane, ethanol, ethyl acetate, ethylene dichloride, methanol, methyl acetate, methyl t-butyl ether, methyl formate, 2-propanol, toluene and xylene and mixture thereof.
The present invention also relates to a herbal composition A herbal composition for the treatment of chronic obstructive pulmonary disease, bronchitis and respiratory disorders comprising:
Bryonia
100-75%
Ipecacuanha
Drosera
and
Antimony potassium tartrate
0-25%
The fruit and the roots of the plant material of the plant Bryonia are used. Only roots of the plant material of the plant Ipecacuanha and Drosera are used.
The antimony potassium tartrate used is of the formula C
8
H
4
K
2
O
12
Sb
2
3H
2
O having molecular weight 667.86
The said extracted materials used in the formation of composition with antimony potassium tartrate are in the following proportion by wt.:
Bryonia
100-75%
Ipecacuanha
Drosera
and
Antimony potassium tartrate
0-25%
or
The said extracted materials used in the formation of composition with antimony potassium tartrate are in the following proportion by wt.:
Bryonia
90-80%
Ipecacuanha
Drosera
and
Antimony potassium tartrate
10-20%
or
The said extracted materials used in the formation of composition with antimony potassium tartarate are in the following proportion by wt.:
Bryonia
25%
Ipecacuanha
25%
Drosera
25%
and
Antimony potassium tartrate
25%
or
The said extracted materials used in the formation of composition with antimony potassium tartarate are in the following proportion by wt.:
Bryonia
35%
Ipecacuanha
25%
Drosera
30%
and
Antimony potassium tartrate
10%
or
The said extracted materials used in the formation of composition with antimony potassium tartarate are in the following proportion by wt.:
Bryonia
Ipecacuanha
100-75%
and
Antimony potassium tartrate
0-25%
or
The said extracted materials used in the formation of composition with antimony potassium tartarate are in the following proportion by wt.:
Bryonia
35%
Ipecacuanha
45%
and
Antimony potassium tartrate
20%
or
The said extracted materials used in the formation of composition with antimony potassium tartrate are in the following proportion by wt.:
Bryonia
90-80%
Ipecacuanha
and
Antimony potassium tartrate
10-20%
or
The said extracted materials used in the formation of composition with antimony potassium tartrate are in the following proportion by wt.:
Bryonia
40%
Ipecacuanha
45%
and
Antimony potassium tartrate
15%
or
The said extracted materials used in the formation of composition with antimony potassium tartrate are in the following proportion by wt.:
Bryonia
100-75%
Drosera
and
Antimony potassium tartrate
0-25%
or
The said extracted materials used in the formation of composition with antimony potassium tartrate are in the following proportion by wt.:
Bryonia
35%
Drosera
55%
and
Antimony potassium tartrate
10%
or
The said extracted materials used in the formation of composition with antimony potassium tartrate are in the proportion by wt.:
Ipecacuanha
100-75%
Drosera
and
Antimony potassium tartrate
0-25%
or
The said extracted materials used in the formation of composition with antimony potassium tartrate are in the proportion by wt.:
Ipecacuanha
35%
Drosera
45%
and
Antimony potassium tartrate
20%
The description of plants is given below for easy identification. It is important that the right species is identified correctly for this preparation.
Bryonia—(Kattuthumatikai)
Description of Plants
Perennial scabrid monecious tendrillar herb with slender angled stem; leaves depply, palmately five lobed, scabrid on both sides, hispid on the tlerves beneath and rounded at the apex; the male flowers yellow in small clusters on slender globosc; fruits ellipsoid or sub-globosc, yellow or yellow with green stripes; seeds while, ellipsoid.
Ipecacuanha—(Poaya)
Description of Plants
Half-shrubby perennial, roots several, scarcely branched, orange-brown. Leaves few, somewhat crowded at the upper part of the stem, opposite, shortly stalked, stipples large, united at the base, where are several ovoid glands, persistent, pressed to the stem, whitish, about as long as the petiole, deeply cut into four subulate aciniae, blade 24 inches long or more, oval, acute or blunt at the apex, entire and more or less wavy on the margin, thick, with a few hairs on the edge, dark green and nearly smooth above, pal
Dalmia Centre for Biotechnology
Jain Mishrilal
Lilling Herbert J.
LandOfFree
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