Herbal chemical composition for the treatment of cancer

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C424S725000, C514S461000, C514S473000

Reexamination Certificate

active

10463060

ABSTRACT:
The present invention relate to a novel synergistic composition of lignans exhibiting anticancer activities for breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate cancer obtained from the plant extract ofCedrus deodra, said composition comprising of (−)-Matairesinol in the range of 9 to 13% by weight, (−)-Wikstromol in the range of 75 to 79% by weight, Dibenzylbutyrolactol in the range of 7 to 11% by weight, and Unidentified material in the range of 2.6 to 3% by weight; further, the synergistic composition of lignan is used in combination with pharmaceutically acceptable carriers for inhibiting growth of various human cancer cell lines selected from breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate tissues.

REFERENCES:
patent: 6271257 (2001-08-01), Mutanen
patent: 6458831 (2002-10-01), Rao et al.
patent: 6537593 (2003-03-01), Rao et al.
patent: 6649650 (2003-11-01), Rao et al.
Ingram et al “Case-control study of phyto-oestrogens and breast cancer” The Lancet vol. 350 Iss 9083 Oct. 4, 1997 pp. 990-994.
Watanabe et al Abs of “Intake of phytoestrogen and prevention of cancer” AN 1997:369167 CAPLUS DN 127:80731.

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