HER-2/neu fusion proteins

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S070100, C435S069100, C435S070300, C435S072000, C536S023400, C536S023500, C514S04400A

Reexamination Certificate

active

09493480

ABSTRACT:
The present invention is generally directed to HER-2
eu fusion proteins, nucleic acid molecules encoding HER-2
eu fusion proteins, viral vectors expressing HER-2
eu fusion proteins, and pharmaceutical compositions (e.g., vaccines) comprising the HER-2
eu fusion proteins and/or nucleic acid molecules encoding the HER-2
eu fusion proteins. The present invention is also directed to methods of treating or preventing cancer by eliciting or enhancing an immune response to the HER-2
eu protein, including for uses in the treatment of malignancies associated with the HER-2
eu oncogene.

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