Hepatocyte growth factor to treat glaucoma

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514913, A61K 3800

Patent

active

056864078

ABSTRACT:
Methods for controlling IOP with compositions of HGF Receptor Activators are disclosed.

REFERENCES:
patent: 5589451 (1996-12-01), Wilson
Boros, et al., The Lancet, Hepatocyte growth factor: a multifunctional cytokine, 345, 293-295 (Feb. 4, 1995).
Rosen, et al., The Journal of Cell Biology, Scatter Factor and the c-Met Receptor: A Paradigm for Mesenchymal/Epithelial Interaction, vol. 127, No. 6, Part 2, 1783-1787 (Dec., 1994).
Wilson, et al., Exp. Eye Res., Effect of Epidermal Growth Factor, Hepatocyte Growth Factor, and Keratinocyte Growth Factor, on Proliferation, Motility and Differentiation of Human Corneal Epithelial Cells, 59, 665-678 (1994); and.
Clark, et al., Investigative Ophthalmology & Visual Science, Glucocorticoid-Induced Formation of Cross-Linked Actin Networks in Cultured Human Trabecular Meshwork Cells, 35:1, 281-294 (Jan. 1994).
Lyon, et al., Biochemical Society Transactions, Hepatocyte Growth Factor/Scatter Factor: A Heparan Sulphate-Binding Pleiotropic Growth Factor, vol. 22, No. 2, 365-370 (1994); and.
Vigna, et al., Cellular and Molecular Biology, Hepatocyte Growth Factor and Its Recetor, the Tyrosine Kinase Encoded by the c-Met Proto-Oncogene, vol. 40, No. 5, 597-604 (1994).

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