Hepatocyte growth factor receptor antagonist antibodies and uses

Details Hepatocyte growth factor receptor antagonist antibodies and uses Hepatocyte growth factor receptor antagonist antibodies and uses

1995-06-02

1997-11-11

Feisee, Lila

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4241331, 4241431, 5303873, 5303877, 5303881, 5303882, 53038822, 5303888, 53038885, 5303891, 5303897, C12N 512, A61K 39395, C07K 1628

Patent

active

056862920

ABSTRACT:
Hepatocyte growth factor (HGF) receptor antagonists are provided. The HGF receptor antagonists include HGF receptor antibodies and fragments thereof. The HGF receptor antagonists can be employed to block binding of HGF to HGF receptors or substantially inhibit HGF receptor activation. The HGF receptor antagonists may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treating cancer using the HGF receptor antagonists are also provided.

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