Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1993-10-08
1996-07-02
Knode, Marian C.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
43524021, 43524023, 435240243, C12N 500
Patent
active
055321569
ABSTRACT:
Continuous cultures of pluripotent parenchymal hepatocytes were derived from the epiblasts of pig blastocysts. The cultures are feeder-dependent and grow slowly with doubling times of 3 to 4 days. They differentiate into large secretory duct-like structures or form small canaliculi. Alternatively, the cells accumulate droplets that stain intensely with oil red O, a lipid-specific stain. .alpha.-Fetoprotein and albumin mRNA expression increases as the cells differentiate in culture.
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Powell Anne M.
Pursel Vernon G.
Rexroad, Jr. Caird E.
Talbot Neil
Dadio Susan M.
Fado John
Graeter Janelle S.
Knode Marian C.
Silverstein M. Howard
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