Hepatocellular carcinoma oncogene

Details Hepatocellular carcinoma oncogene Hepatocellular carcinoma oncogene

1991-10-15

1995-04-04

Fleisher, Mindy B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 935 77, 935 78, C07H 2102, C07H 2104, C12Q 168, C12N 1500

Patent

active

054039266

ABSTRACT:
The present invention relates to an oncoprotein specific for hepatocellular carcinomas and to a nucleotide sequence that codes for such a protein. The invention further relates to screening and diagnostic methodologies (and kits based thereon) that make use of the oncoprotein (or antibodies specific for same) and the nucleotide sequence.

REFERENCES:
Yang et al, Molecular Cloning of the Endogenous Rat C-type Helper Virus DNA Sequence: Structural Organization and Functional Analysis of Some Restricted DNA Fragments, Journal of General Virology, vol. 63, 1982, pp. 25-36.
ENBL Database, Accession #V01511, 1983.
Yang et al; "Transforming DNA Sequences of Human Hepatocellular Carcinomas, Their Distribution and Relationship with Hepatitis B. Virus sequence in Human Hepatomas"; Leukemia, vol. 2, No. 12; Dec. 1988; pp. 102-113.

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