Hepatobiliary NMR contrast agents

Details Hepatobiliary NMR contrast agents Hepatobiliary NMR contrast agents

1985-05-08

1990-02-13

Rosenbaum, C. Fred

Surgery

Truss

Pad

A61K 4300, A61K 4902

Patent

active

048997552

ABSTRACT:
A method of altering proton NMR relaxation times in the liver or bile duct of a human patient involving administering to the patient an agent characterized in that it is taken up preferentially by human hepatocytes, compared to human reticuloendothelial cells, and it contains a paramagnetic substance capable of altering the proton NMR relaxation times in the hepatocytes.

REFERENCES:
patent: 4150047 (1979-04-01), Coe et al.
patent: 4308249 (1981-12-01), Frank et al.
patent: 4331647 (1982-05-01), Goldenberg
patent: 4352751 (1982-10-01), Wieder et al.
patent: 4361544 (1982-11-01), Goldenberg
patent: 4401647 (1983-08-01), Krohn et al.
patent: 4472509 (1984-09-01), Gansaw et al.
patent: 4615879 (1986-10-01), Ringe et al.
patent: 4639365 (1987-01-01), Sherry
patent: 4647447 (1987-03-01), Gries et al.
Brasch et al., "Contrast-Enhanced NMR Imaging: Animal Studies Using Gadolinium-DTPA Samples" in AJR 142, pp. 625-630, Mar. 1984.
Felix et al., "Brain Tumors NMR Imaging with Gadolinium DTPA" in Radiology 56, 681-88 (1985).
Unger et al., "Magnetic Resonance Imaging Using Gd-Labeled Monoclonal Antibody," Invert. Radiology 20, (1985) pp. 693-700.
Chen C., Cohen J. S., Myers C. E. and John M., Paramagnetic Metalloporphyrins as Potential Contrast Agents in NMR Imaging in FEBS Letters, vol. 168, No. 1, Mar. 1984, pp. 70-74.
Weinman et al., Characteristics of Gadolinium-DTPA Complex, A Potential NMR Contrast Agent in AJR Mar. 1984, pp. 619-624.
Haddock et al. Proc. Soc. Exptl. Biol. Med. 120:663 (1965).
Bagley et al. Proc. Soc. Exptl. Biol. Med. 127:798 (1968).

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