Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1996-04-24
1998-06-16
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435 691, 435 697, 530324, 530826, 536 232, 536 2372, C12N 950, C12P 2106, C12P 2104, C07H 2104
Patent
active
057669163
ABSTRACT:
The protease necessary for polyprotein processing in Hepatitis G virus (HGV) is identified, cloned, and expressed. Proteases, truncated protease, and altered proteases are disclosed which are useful for cleavage of specific polypeptides, and for assay and design of antiviral agents specific for HGV.
REFERENCES:
Leary, T.P., et al., "Sequence and Genomic Organization of GBV-C: A Novel Member of the Flaviviridae Associated with Human Non-A-E Hepatitis," Journal of Medical Virology 48(1):60-67 (1996).
Belyaev Alexander S.
Chong Susan M.
Brookes Allan A.
Evans Susan T.
Genelabs Technologies, Inc.
Slobodyansky Elizabeth H.
Wax Robert A.
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