Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1995-06-05
1998-06-16
Knode, Marian C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
5303883, 5303894, C12Q 170, C07K 1610
Patent
active
057668400
ABSTRACT:
Polypeptide antigens are disclosed which are immunoreactive with sera from individuals having a non-A, non-B, non-C, non-D, non-E Hepatitis, herein designated Hepatitis G Virus (HGV). Corresponding genomic-fragment clones containing polynucleotides encoding the open reading frame sequences for the antigenic polypeptides are taught. The antigens are useful in diagnostic methods for detecting the presence of HGV in test subjects. The antigens are also useful in vaccine and antibody preparations. In addition, the entire coding sequences of two HGV isolates are disclosed. Methods are presented for nucleic acid-based detection of HGV in samples and also methods for the isolation of further genomic sequences corresponding to HGV.
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Fry Kirk E.
Kim Jungsuh P.
Linnen Jeffrey M.
Wages John
Young LaVonne Marie
Brumback Brenda Glass
Dehlinger Peter J.
Evans Susan T.
Fabian Gary R.
Genelabs Technologies, Inc.
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