Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1996-09-06
1998-01-27
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435 23, 435 691, 435 697, 4352523, 43525233, 4353201, 536 232, 536 234, 536 2372, 935 14, 935 32, 935 70, 935 73, 935 79, C12N 950, C12N 1557, C12N 1562, C12Q 137
Patent
active
057121451
ABSTRACT:
The protease necessary for polyprotein processing in Hepatitis C virus is identified, cloned, and expressed. Proteases, truncated protease, and altered proteases are disclosed which are useful for cleavage of specific polypeptides, and for assay and design of antiviral agents specific for HCV.
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Choo Qui-Lim
Houghton Michael
Kuo George
Blackburn Robert P.
Chiron Corporation
Goldman Kenneth M.
Harbin Alisa A.
Moore William W.
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