Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2011-02-22
2011-02-22
Peng, Bo (Department: 1648)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S005000, C435S007210, C424S184100, C424S189100
Reexamination Certificate
active
07892754
ABSTRACT:
The invention relates to a group of synthetic polypeptides, derived from the pre-S1 region of HBV, that efficiently interfere with early steps of an HBV infection. The peptides of the invention can be used in diagnostics for the detection of antigens and/or antibodies.
REFERENCES:
patent: 5158769 (1992-10-01), Neurath et al.
Kramvis A, Kew MC. “Relationship of genotypes of hepatitis B virus to mutations, disease progression and response to antiviral therapy.” J Viral Hepat. Sep. 2005;12(5):456-64.
Gripon P, et al. “Efficient inhibition of hepatitis B virus infection by acylated peptides derived from the large viral surface protein.” J Virol. Feb. 2005;79(3):1613-22.
Keller, MA, “Passive immunity in prevention and treatment of infectious disease.” Clin Microbiol Rev. Oct. 2000;13(4):602-14.
Engelke et al. “Characterization of a hepatitis B and hepatitis delta virus receptor binding site.” Hepatplogy, Apr. 2006;43(4):750-60.
Kidd-Ljunggren K, et al. “Generic variability in hepatitis B viruses.” J Gen Virol. Jun. 2002;83(Pt 6):1267-80. Review.
Neurath AR et al. “Identification and chemical synthesis of a host cell receptor binding site on hepatitis B virus” Cell, 46:429-436, 1986.
Gripon Philippe
Urban Stephan
Institut National de la Sante Et de la Recherche Medicale (INSER
Peng Bo
Schulman B. Aaron
Stites & Harbison PLLC
Urban Stephen
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