Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1995-05-23
1999-07-20
Wortman, Donna C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 792, 436518, 436820, 5303879, 5303883, C12Q 170, G01N 3353, G01N 33543, G01N 33576
Patent
active
059255129
ABSTRACT:
Mutant Hepatitis B Virus (HBV) nucleic acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HBV nucleic acid sequences, HBV immunogenic particles, and a method for producing antibodies to HBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HBV nucleic acid sequences.
REFERENCES:
patent: 4871659 (1989-10-01), Pillot
patent: 5279944 (1994-01-01), Fabrizi et al.
patent: 5565354 (1996-10-01), Ostberg
patent: 5591440 (1997-01-01), Carman et al.
patent: 5593825 (1997-01-01), Carman et al.
patent: 5595739 (1997-01-01), Carman et al.
Okamoto et al., "The Loss of Subtypic Determinants in Alleles, d/y or w/r, on Hepatitis B Surface Antigen", Mol. Immunol. 26, 197-205, 1989.
Yamamoto et al., "Naturally Occuring Escape Mutants of Hepatitis B Virus with Various Mutations in the S Gene in Carriers Seropositive for Antibody to Hepatitis B Surface Antigen", J. Virol. 68, 2671-2676, 1994.
William Carman, et al, "Viral genetic variation: hepatitis B virus as a clinical example" The Lancet, vol. 341:349-353 (1963).
William F. Carman, et al, "Vaccine-induced escape mutant of hepatitis B virus." Medical Science vol. 336:325-329 (1990).
Tim J. Harrison et al., "Variants of Hepatitis B Virus" Vox Sang 1992;63:161-167.
Philip G. Ashton-Rickardt et al., "Mutants of the Hepatitis B Virus Surface Antigen That Define Some Antigenically Essential Residues in the Immunodominant a Region" Journal of Medical Virology 29:196-203 (1989).
K. Yamamoto, et al., "Naturally Occurring Escape Mutants of Hepatitis B Virus with Various Mutations in the S Gene in Carriers Seropositive for Antibody to Hepatitis B Surface Antigen", J. Virol., vol. 68 No. 4:2671-2676 (1994).
W.F. Carman, et al., "Genetic Variation in Hepatitis B Virus", Gastroenterology, vol. 102:711-719 (1992).
Tabor et al., "Transmission of Non-A, Non-B Hepatitis from Man to Chimpanzee", Lancet 1, 463-466 (1978).
Carman William F.
Decker Richard H.
Mimms Larry T.
Solomon Larry R.
Wallace Lesley
Abbott Laboratories
Casuto Dianne
Porembski Priscilla E.
Williams Jay
Wortman Donna C.
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