Hepatitis B monoclonal antibodies

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S388800

Reexamination Certificate

active

09402282

ABSTRACT:
A monoclonal antibody that is capable of binding specifically to wild type HBsAg and to at least two mutant forms of HBsAg may be used in an improved immunoassay for the detection of both escape mutants and wild type HBsAg and may be used for passive immunisation against HBV.

REFERENCES:
patent: 94/21812 (1994-09-01), None
Mangold CM et al. “Secretion and antigenicity of hepatitis B virus small envelope proteins lacking cysteines in the major antigenic region”. Virology. Aug. 20, 1995; 211(2):535-43.

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