Hepatitis B immune globulin used to inactivate hepatitis B virus

Details Hepatitis B immune globulin used to inactivate hepatitis B virus Hepatitis B immune globulin used to inactivate hepatitis B virus

1980-04-11

1982-08-24

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

424 85, 260112B, A61K 3942

Patent

active

043460739

ABSTRACT:
The utilization of hepatitis B immune globulin as a preparation for preventing transmission of the hepatitis B virus (HBV) by injectable biologics, by incubation of the injectable biologics and hepatitis B immune globulin together in vitro prior to administration to patient. The hepatitis B immune globulin is utilized in a dosage of 5 ml and in a preferred titer of 1 to 100,000. The titer may vary to a range of 1 to 100 concentration with an intermediate range of 1 to 1,000 ranging down to 1 to 100,000. Also there may be used other immune globulins such as immune serum globulin (ISG).

REFERENCES:
patent: 4021540 (1977-05-01), Pollack et al.
patent: 4087519 (1978-05-01), Trepo
patent: 4174388 (1979-11-01), McAleer et al.
Tabor et al., "A New Use for High Titer Immunoglobulin for the Prevention of Hepatitis B", Hepatitis Scientific Memoranda, Nov. 1979.
Tabor et al., "A New Use for High Titer Immunoglobulin, for the Prevention of Hepatitis B", Proceeding of Immunology Workshop, Oct. 1979.

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