Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1977-09-02
1978-10-03
Rosen, Sam
Drug, bio-affecting and body treating compositions
Lymphokine
A61K 3912
Patent
active
041184777
ABSTRACT:
An improved process for the preparation of hepatitis B antigen by subjecting biological fluid containing heptatitis B surface antigen to isopycanic banding wherein the step gradient is NaBr. Faster and more economical processing is obtained by multiple loading of the step gradient, either NaBr or conventional gradients.
REFERENCES:
patent: 3519400 (1970-07-01), Anderson
patent: 3636191 (1972-01-01), Blumberg et al.
patent: 3838144 (1974-09-01), Leach
Bond et al.--J. Inf. Dis., vol. 125, Mar. 1972.
McAleer William J.
Wasmuth Edward H.
Merck & Co. , Inc.
Perrella Donald J.
Rosen Sam
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