Hepatitis B antigen

Details Hepatitis B antigen Hepatitis B antigen

1979-04-04

1980-12-30

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Lymphokine

A61K 3929

Patent

active

042423244

ABSTRACT:
An improved process for the preparation of hepatitis B antigen by subjecting plasma of hepatitis B donors to isopycanic banding wherein the step gradient is NaBr. Faster and more economical processing is obtained by multiple loading of the step gradient, either NaBr or conventional gradients.

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Gerin et al., J. Virol., 4(5): 763-768, (1969), Biophysical Properties of Australia Antigen.
Bond et al., J. Inf. Dis., 125(3): 263, Mar. 1972, Separation and Purification of Hepatitis-Associated Antigen into Morphologic Types by Zonal Ultracentri Fugation.
Gerin et al., J. Virol, 7(5): 569-576, (1971), Australia Antigen: Large-Scale Purification from Human Serum and Biochemical Studies of Its Proteins.
Millman et al., J. Exp. Med., 131: 1190-1199, (1970), Australia Antigen A Hepatitis-Associated Antigen.

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