Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Reexamination Certificate
2005-09-13
2005-09-13
Scheiner, Laurie (Department: 1648)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
C435S006120, C536S023100, C536S023720
Reexamination Certificate
active
06942965
ABSTRACT:
Hepatitis A virus primers and probes derived from the capsid proteins and junction between the capsid precursor P1 and 2A of the HAV genome are disclosed. Also disclosed are nucleic acid-based assays using the primers and probes, antigen detection of HAV, and immunoassay for detecting the antibodies that bind to HAV.
REFERENCES:
patent: 5516630 (1996-05-01), Ticehurst et al.
Cohen et al., “Complete Nucleotide Sequence of Wild-Type Hepatitis A Virus: Comparison with Different Strains of Hepatitis A Virus and Other Picomaviruses,”J. Virology61(1):50-59, 1987.
Locarnini et al., “Restricted replication of human hepatitis A virus in cell Culture: intracellular biochemical studies,”J. Virol.37:216-225, 1981.
Siegl et al., “The physicochemical properties of infectious hepatitis A virions,”J. Gen. Virol.57:331-341, 1981.
Nguyen Steve H.
Pichuantes Sergio
Blackburn Robert P.
Chiron Corporation
Lillis Marcella
Robins Roberta L.
Scheiner Laurie
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