Hepatic disturbance improver

Details Hepatic disturbance improver Hepatic disturbance improver

1999-05-10

2000-07-04

Krass, Frederick

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 54, 514 61, 514 25, 514893, 53612303, A01N 4304

Patent

active

060839279

ABSTRACT:
A hepatic disturbance improver which reduces fat in hepatocytes which includes an oligosaccharide of formula (1), (2) or (3), obtainable by hydrolyzing porphyran contained in seaweed of the genus Porphyra. The hepatic disturbance improver is advantageous, in that it reduces fat in hepatocytes without causing side effects.

REFERENCES:
patent: 5063210 (1991-11-01), Lange et al.
patent: 5160736 (1992-11-01), Kiriyama et al.
Harrison's Principles of Internal Medicine, McGraw-Hill Inc., 13th edition, chapter 270, p. 1498, 1994.
Yukihiro Osumi et al, "Purification and Characterization of Porphyran-Decomposing Enzymes from Arthrobacter sp. S-22," Nippon Suisan Gakkaishi 63(5), 757-764(1997) (with English abstract).
Yukihiro Osumi et al, "Isolation and Identification of a Porphyran-Decomposing Bacterium," Nippon Suisan Gakkaishi 63(4), 709-714 (1997) (with English Abstract).
Yukihiro Osui et al, "Purification and Structure of Oligosaccharides from Porphyran degraded by Enzymes from Arthrobacter sp. S-22, " Nippon Suisan Gakkaishi 64(1), 88-97 (1998) (with English Abstract).
Yukihiro Osumi et al, "Effect of Oligosaccharides from Porphyan o In Vitro Digestions, Utilizations by Various Intestinal Bacteria, and Levels of Serum Lipid in Mice," Nippon Suisan Gakkaishi 64(1), 98-104-(1998) (with English Abstract).

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