Heparinase produced by microorganism belonging to the genus baci

Details Heparinase produced by microorganism belonging to the genus baci Heparinase produced by microorganism belonging to the genus baci

1989-11-22

1992-09-08

Marx, Irene

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Lyase

435 712, 4352525, C12N 988, C12N 120, C12P 2100

Patent

active

051457784

ABSTRACT:
A newly discovered microorganism is described that was isolated in biologically pure culture from soil and designated Bacillus sp. strain BH100 (FERM BP-2613 (FERM P-10408)). This strain is used in a new process for production of extracellular heparinase. Additionally a new heparinase having an optimum temperature for activity in the range of 45.degree. to 50.degree. C. is disclosed.

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Linker et al. In Methods in Enzymology, vol. 28, pp. 902-911, 1972.
Nakamura et al., J. of Clinical Microbiol., vol. 26, p. 1070, 1988 (May).

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