Heparin purification method

Details Heparin purification method Heparin purification method

1977-03-02

1978-10-10

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

A61K 31725

Patent

active

041197747

ABSTRACT:
Crude clinically used heparin preparations having a low specific activity, for example, about 130 heparin units per milligram are purified by contacting such liquid crude heparin preparations with a gel matrix complexed with (i.e. having linked to it) antithrombin or inter-alpha-trypsin inhibitor as a heparin-binding plasma protein, and then desorbing or eluting the heparin from the antithrombin or inter-alpha-trypsin inhibitor complexed gel matrix as with an applicable buffer, removing any salt in the solution with the heparin by gel filtration and then drying the heparin as by lyophilization.

REFERENCES:
patent: 2623001 (1952-12-01), Sylven et al.

Affiliated with

Also associated with

Rating

Heparin purification method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Heparin purification method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heparin purification method will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1767480