Heparin polyelectrolyte polymer complex

Details Heparin polyelectrolyte polymer complex Heparin polyelectrolyte polymer complex

1983-01-24

1984-09-11

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424101, 424183, C08B 3710

Patent

active

044711123

ABSTRACT:
A concentrate of blood coagulation Factor VIII:C is obtained in high yield by fractionation of blood plasma with a sequence of adsorption steps employing two different water-insoluble, cross-linked polyelectrolyte copolymers, each in the presence of exogenous heparin.

REFERENCES:
patent: 3555001 (1971-01-01), Wallis et al.
patent: 4157431 (1979-06-01), Fields et al.
patent: 4291133 (1981-09-01), Horak et al.
Nakajima et al., "Bull. Inst. Chem. Res.," Kyoto Univ., vol. 52, Nos. 5-6, Nov. 1974.
Johnson et al., J. Lab. Clin. Med., 92, 1978, pp. 194-210.

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