Heparin neutralization with platelet factor 4 fragments

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 12, 514 13, 514 14, 514 15, 514 16, 514 17, A61K 3836, A61K 3808

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054829232

ABSTRACT:
Circulating heparin in a mammal may be neutralized without substantial depletion of platelets or leukocytes by administering to the mammal a heparin neutralizing amount of a purified heparin binding fragment of PF4 or of recombinant PF4.

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