Heparin-like derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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Details

514822, 536 21, A61K 31725, C08B 3710

Patent

active

058721100

ABSTRACT:
The invention relates to carbohydrate derivatives having the formula I, ##STR1## wherein R.sup.1 is H or CH.sub.2 OSO.sub.3.sup.-, R.sup.2 and R.sup.3 are independently H, (1-6C)alkyl or SO.sub.3.sup.- ; R.sup.4 is OSO.sub.3.sup.- or NHSO.sub.3.sup.- ; n is 0 or 1; p is 1 or 2; or a pharmaceutically acceptable salt thereof The compounds of the invention have antithrombotic activity and may be used for inhibiting smooth muscle cell proliferation.

REFERENCES:
patent: 5514659 (1996-05-01), Petitou et al.
patent: 5543403 (1996-08-01), Petitou et al.
patent: 5707973 (1998-01-01), Baron et al.

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