Heparin fragments having selective anticoagulation activity

Details Heparin fragments having selective anticoagulation activity Heparin fragments having selective anticoagulation activity

1980-01-04

1981-12-01

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated to proteinaceous toxin or fragment thereof

536 21, A61K 31725, C08B 3710

Patent

active

043036511

ABSTRACT:
Heparin fragments having selective anticoagulation activity having 14-18 sugar units, the disaccharide unit L-iduronosyl-2-O-sulphate-N-sulpho-U-glucosamine-6-O-sulphate being the main component, and where unsulphated L-iduronic acid is in a position situated 3-5 sugar units from the unreducing terminal. Pharmaceutical compositions containing such heparin fragments. Processes for the preparation of the heparin fragments.

REFERENCES:
patent: 3066076 (1962-11-01), Monnier
patent: 3135660 (1964-06-01), Bush et al.
patent: 3810781 (1974-05-01), Eriksson et al.
patent: 3835112 (1974-09-01), Mardiguian et al.
patent: 3891622 (1975-06-01), Mardiguian et al.

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