Heparin fragments as inhibitors of smooth muscle cell proliferat

Details Heparin fragments as inhibitors of smooth muscle cell proliferat Heparin fragments as inhibitors of smooth muscle cell proliferat

1989-08-31

1991-07-16

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 172, 536 175, 536 179, 536 22, 536124, C08B 3700, C07H 500, A61K 3100

Patent

active

050326791

ABSTRACT:
A glycosaminoglycoside (GAG) composition predominantly of tetrasacchardie units derived from heparin/heparan sulfate has enchanced activity in preventing the proliferation of smooth muscle cells. This GAG preparation is useful in the treatment of diseases characterized by unwanted smooth muscle cell proliferation and activity.

REFERENCES:
patent: 4401662 (1983-08-01), Lormeau et al.
Casu, (1985) "Structure and Biological Activity of Heparin" in Advances in Carbohydrate Chemistry and Biochemistry 43:51-134.
Castellot et al., (1986) Journal of Cell Biology 102:1979-1984.
Benitz et al., (1986) Journal of Cellular Physiology 127:1-7.

Affiliated with

Also associated with

Rating

Heparin fragments as inhibitors of smooth muscle cell proliferat does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Heparin fragments as inhibitors of smooth muscle cell proliferat, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heparin fragments as inhibitors of smooth muscle cell proliferat will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-132681