Heparin derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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Details

514822, 536 21, A61K 31725, C08B 3710

Patent

active

048164461

ABSTRACT:
The invention comprises heparin derivative compounds which possess a low density lipoprotein lowering action without a significant anticoagulent effect, and are therefore useful in the treatment of disturbances of fat metabolism, especially hyperlipidemia. The heparin derivatives of the invention are derived from natural heparin, and are prepared by the hydrolysis of heparin and optionally, subsequent acylation at free amine groups of the hydrolyzed heparin.

REFERENCES:
patent: 3118816 (1964-01-01), Cushing
patent: 3151025 (1964-09-01), Costello

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