Heparin and hirudin antidotal compositions and methods

Details Heparin and hirudin antidotal compositions and methods Heparin and hirudin antidotal compositions and methods

1991-09-20

1993-04-20

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 12, 514 56, 514 54, 514834, 530383, A61K 3702, A61K 31725

Patent

active

052043231

ABSTRACT:
The invention provides an antidote to blood anticoagulants comprising Factor VIII or fragments of Factor VIII which retain its activity or a substance which increases its concentration in blood.

REFERENCES:
patent: 4789733 (1988-12-01), Winkelman
patent: 4929602 (1990-05-01), Harker et al.
Agnelli et al.; Chemical Abstracts 111(15):1273825 (1989).
Palmer et al.; Chemical Abstracts 109(25):222834h (1988).
Koehler et al.; Chemical Abstracts 109(7):512220 (1988).
Rock et al.; Chemical Abstracts 95(19):162771r (1981).
Rock et al.; Vox Sang. 41:56-60 (1981).
Palmer et al.; Transfusion 28(4):311-315 (1988).
Agnelli et al; Thrombosis and Haemostasis 61(3):507-510 (1989).
Thrombos. Diather Haemorrh. vol. 14, No. 32 p. 32 (1965).
Textbook of Medical Physiology, Arthur C. Guytan, MD pp. 140-141.
Clinical Science 67, 561-567 (1984) Peake.
Nature 312, 337-342 (1984) Vehar et al.
Critical Reviews Ancol./Hermatol. 6, 19-54 (1985) Hamer et al.
Clinical Pharma cokinetics 13, 365-380 Messori et al. (1987).
Blut 56, 171-178(1988) Fukui et al.
Hemeostasis and Thrombosis 8, 19-45 (1986) Mannucci.
Amer. J. Hematol 30, 154-157 (1989) Wigermans et al.
Amer. J. Hematol 31, 32-35 (1989) Vigano et al.
Pharma zeutische Chemie (1982) Schroder et al. pp. 650-659.
The Lancet 1,1145-1148 (1984) Kobrinsky et al.
Die Pharmayie 36, 653-660 (1981).

Affiliated with

Also associated with

Rating

Heparin and hirudin antidotal compositions and methods does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Heparin and hirudin antidotal compositions and methods, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heparin and hirudin antidotal compositions and methods will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1526155