Hemolytic method for the kinetic determination of antistreptolys

Details Hemolytic method for the kinetic determination of antistreptolys Hemolytic method for the kinetic determination of antistreptolys

1981-06-22

1983-04-12

Marantz, Sidney

Chemistry: analytical and immunological testing

Involving kinetic measurement of antigen-antibody reaction

436522, 436805, G01N 3354

Patent

active

043798500

ABSTRACT:
The hemolytic method for the kinetic determination of antistreptolysin O antibodies (ASO) in blood samples consists of reacting a first reagent containing a single dose of oxidized SO with the specific antibodies which may be present in the blood sample under examination, allowing the necessary time to pass for the reaction between the oxidized SO and said antibodies to take place, returning the oxidized SO to its reduced state by adding a second reagent, and measuring the rate of hemolysis. The kinetic determination of the ASO titre is obtained by comparing said rate of hemolysis with the rate of hemolysis shown graphically for samples of known ASO titre.

REFERENCES:
patent: 4148609 (1979-04-01), Ricci

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