Hemoglobins provided with ligands protecting the oxygen binding

Details Hemoglobins provided with ligands protecting the oxygen binding Hemoglobins provided with ligands protecting the oxygen binding

1998-01-09

1999-11-16

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Blood

514832, A61K 3514

Patent

active

059853328

ABSTRACT:
Artificial oxygen carrier composed of native or modified hemoglobins for direct biological or medical use, in which the oxygen binding site of the hemoglobin is provided with a protective ligand, preferably carbon monoxide, which does not have to be removed prior to use.

REFERENCES:
patent: 5171755 (1992-12-01), Kaufman et al.
Ikedo-Saito et al. J. Mol. Biol., 138(4), 845-58 (Abstract), 1980.
Muirhead et al. J. Hypertens., 10(9), 963-7 (Abstract), 1992.

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