Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1978-05-01
1981-01-27
Padgett, Benjamin R.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
422 61, 424 12, 23230B, G01N 3348, G01T 100, B65D 7100
Patent
active
042475333
ABSTRACT:
Sheep antiserum developed against the human glycohemoglobin, Hb A.sub.1c, distinguishes this fraction from the major component Hb A.sub.o. Partial cross relativity is observed with Hb A.sub.1a and Hb A.sub.1b, as well as with analogous glycohemoglobins from mouse and dog hemolysates. The reactivity of the hemoglobins with this specific antiserum is abolished by the reduction of the keto group of the sugar ligand. The immunological specificity displayed provides the basis of a quantitative assay for Hb A.sub.1c, which is suitable for studies of clinical and experimental diabetes.
REFERENCES:
Gabbay et al., J. Clin. End. Met., vol. 44, No. 5, May 1977, pp. 859-864.
Garver et al., Chem. Abstracts, vol. 83, Sep. 1, 1975, Abstract No. 75030g.
Cerami Anthony
Javid Jamshid
Koenig Ronald J.
Pettis Penelope K.
Nucker Christine M.
Padgett Benjamin R.
The Rockefeller University
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