Liquid purification or separation – Processes – Including controlling process in response to a sensed condition
Patent
1996-04-29
1997-09-02
Drodge, Joseph W.
Liquid purification or separation
Processes
Including controlling process in response to a sensed condition
204406, 2057805, 210 93, 210 962, 210646, 436108, 604 4, B01D 6132
Patent
active
056628064
ABSTRACT:
An improved on-line real time hemodialysis monitoring system for hemodialysis treatment. The hemodialysis monitoring system quantitates the rate and amount of a constituent, such as urea, removed during the hemodialysis treatment by measuring the constituent concentrations as a function of time in the spent dialysate effluent from a hemodialysis machine. A quantity of the spent dialysate effluent is removed from the dialysate effluent waste line periodically for testing. A urea concentration time profile can be analyzed to determined the urea removal, KT/V, URR, SRI and normalized protein catabolic rate (nPCR) indices. The hemodialysis monitoring system preferably can obtain a dialysate sample equilibrated with the blood prior to the start of a hemodialysis treatment. The hemodialysis monitoring system includes a two pool analysis for taking into account the constituent concentration differences in the extracellular and intracellular spaces in the hemodialysis patient during the hemodialysis treatment.
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Blackwell Scientific Publications, Inc., Artificial Organs, "Kt/V and protein Catabolic Rate Determination from Serial Urea Measurement in the Dialysate Effluent Stream," Laurie J. Garred, Bonny DiGiuseppe, Winston Chand, William McCready, and Bernard Canaud, pp. 248-255, Feb. 1992.
Ebben James P.
Emerson Paul F.
Keshaviah Prakash
Luhring David A.
Baxter International Inc.
Borecki Thomas S.
Cortina Anibal Jose
Drodge Joseph W.
Mattenson Charles R.
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