Coating processes – Medical or dental purpose product; parts; subcombinations;...
Reexamination Certificate
2004-04-05
2010-10-05
Meeks, Timothy H (Department: 1715)
Coating processes
Medical or dental purpose product; parts; subcombinations;...
C427S002240, C427S002250, C623S001430, C604S266000
Reexamination Certificate
active
07807210
ABSTRACT:
The present invention relates to providing a porous, hydrophobic polymer with a hemocompatible substance and to the materials produced thereby. One embodiment of the present invention relates to the providing of expanded poly(tetrafluoroethylene) with one or more complexes of heparin, typically containing heparin in combination with a hydrophobic counter ion. The hemocompatible substance is dissolved in a mixture of solvents in which a first solvent wets the polymer to be coated and the second solvent enhances the solubility of the hemocompatible substance material in the solvent mixture. Typical first solvents wetting hydrophobic polymers include non-polar such as hydrochlorofluorocarbons. Typical second solvents include polar solvents such as organic alcohols and ketones. Azeotropic mixtures of the second solvent in the first solvent are used in some embodiments of the present invention although second solvents may be employed in a range of concentration ranges from less than 0.1% up to saturation. A typical example providing a heparin complex to an endoluminal stent, consisting of coating DURAFLO onto an ePTFE stent-covering material.
REFERENCES:
patent: 2072303 (1937-03-01), Herrmann et al.
patent: 2386454 (1945-10-01), Frosch et al.
patent: 3773737 (1973-11-01), Goodman et al.
patent: 3849514 (1974-11-01), Gray, Jr. et al.
patent: 3953566 (1976-04-01), Gore
patent: 4045365 (1977-08-01), Figiel
patent: 4118485 (1978-10-01), Eriksson et al.
patent: 4187390 (1980-02-01), Gore
patent: 4226243 (1980-10-01), Shalaby et al.
patent: 4329383 (1982-05-01), Joh
patent: 4343931 (1982-08-01), Barrows
patent: 4529792 (1985-07-01), Barrows
patent: 4531916 (1985-07-01), Scantlebury et al.
patent: 4611051 (1986-09-01), Hayes et al.
patent: 4654327 (1987-03-01), Teng
patent: 4656242 (1987-04-01), Swan et al.
patent: 4678468 (1987-07-01), Hiroyoshi
patent: 4733665 (1988-03-01), Palmaz
patent: 4745105 (1988-05-01), Griffin et al.
patent: 4745107 (1988-05-01), Foley et al.
patent: 4800882 (1989-01-01), Gianturco
patent: 4871357 (1989-10-01), Hsu et al.
patent: 4882168 (1989-11-01), Casey et al.
patent: 4886062 (1989-12-01), Wiktor
patent: 4895566 (1990-01-01), Lee
patent: 4931287 (1990-06-01), Bae et al.
patent: 4941870 (1990-07-01), Okada et al.
patent: 4977901 (1990-12-01), Ofstead
patent: 5013717 (1991-05-01), Solomon et al.
patent: 5019096 (1991-05-01), Fox, Jr. et al.
patent: 5047020 (1991-09-01), Hsu
patent: 5061738 (1991-10-01), Solomon et al.
patent: 5069899 (1991-12-01), Whitbourne et al.
patent: 5073265 (1991-12-01), Johnson et al.
patent: 5100992 (1992-03-01), Cohn et al.
patent: 5112457 (1992-05-01), Marchant
patent: 5133742 (1992-07-01), Pinchuk
patent: 5135516 (1992-08-01), Sahatjian et al.
patent: 5163952 (1992-11-01), Froix
patent: 5165919 (1992-11-01), Sasaki et al.
patent: 5181903 (1993-01-01), Vann et al.
patent: 5219980 (1993-06-01), Swidler
patent: 5258020 (1993-11-01), Froix
patent: 5272012 (1993-12-01), Opolski
patent: 5292516 (1994-03-01), Viegas et al.
patent: 5298260 (1994-03-01), Viegas et al.
patent: 5300295 (1994-04-01), Viegas et al.
patent: 5306501 (1994-04-01), Viegas et al.
patent: 5306786 (1994-04-01), Moens et al.
patent: 5322659 (1994-06-01), Walder et al.
patent: 5328471 (1994-07-01), Slepian
patent: 5330768 (1994-07-01), Park et al.
patent: 5380299 (1995-01-01), Fearnot et al.
patent: 5383927 (1995-01-01), De Goicoechea et al.
patent: 5417969 (1995-05-01), Hsu et al.
patent: 5417981 (1995-05-01), Endo et al.
patent: 5441759 (1995-08-01), Crouther et al.
patent: 5447724 (1995-09-01), Helmus et al.
patent: 5455040 (1995-10-01), Marchant
patent: 5462990 (1995-10-01), Hubbell et al.
patent: 5464650 (1995-11-01), Berg et al.
patent: 5485496 (1996-01-01), Lee et al.
patent: 5516881 (1996-05-01), Lee et al.
patent: 5525348 (1996-06-01), Whitbourne et al.
patent: 5541167 (1996-07-01), Hsu et al.
patent: 5569463 (1996-10-01), Helmus et al.
patent: 5578073 (1996-11-01), Haimovich et al.
patent: 5584877 (1996-12-01), Miyake et al.
patent: 5605696 (1997-02-01), Eury et al.
patent: 5607467 (1997-03-01), Froix
patent: 5609629 (1997-03-01), Fearnot et al.
patent: 5610241 (1997-03-01), Lee et al.
patent: 5616338 (1997-04-01), Fox, Jr. et al.
patent: 5624411 (1997-04-01), Tuch
patent: 5628730 (1997-05-01), Shapland et al.
patent: 5644020 (1997-07-01), Timmermann et al.
patent: 5649977 (1997-07-01), Campbell
patent: 5658995 (1997-08-01), Kohn et al.
patent: 5667767 (1997-09-01), Greff et al.
patent: 5670558 (1997-09-01), Onishi et al.
patent: 5674241 (1997-10-01), Bley et al.
patent: 5674242 (1997-10-01), Phan et al.
patent: 5679400 (1997-10-01), Tuch
patent: 5700286 (1997-12-01), Tartaglia et al.
patent: 5702754 (1997-12-01), Zhong
patent: 5711958 (1998-01-01), Cohn et al.
patent: 5716981 (1998-02-01), Hunter et al.
patent: 5721131 (1998-02-01), Rudolph et al.
patent: 5723219 (1998-03-01), Kolluri et al.
patent: 5735897 (1998-04-01), Buirge
patent: 5746998 (1998-05-01), Torchilin et al.
patent: 5759205 (1998-06-01), Valentini
patent: 5776184 (1998-07-01), Tuch
patent: 5783657 (1998-07-01), Pavlin et al.
patent: 5788979 (1998-08-01), Alt et al.
patent: 5800392 (1998-09-01), Racchini
patent: 5820917 (1998-10-01), Tuch
patent: 5824048 (1998-10-01), Tuch
patent: 5824049 (1998-10-01), Ragheb et al.
patent: 5830178 (1998-11-01), Jones et al.
patent: 5837008 (1998-11-01), Berg et al.
patent: 5837313 (1998-11-01), Ding et al.
patent: 5849859 (1998-12-01), Acemoglu
patent: 5851508 (1998-12-01), Greff et al.
patent: 5854376 (1998-12-01), Higashi
patent: 5858746 (1999-01-01), Hubbell et al.
patent: 5865814 (1999-02-01), Tuch
patent: 5869127 (1999-02-01), Zhong
patent: 5873904 (1999-02-01), Ragheb et al.
patent: 5876433 (1999-03-01), Lunn
patent: 5877224 (1999-03-01), Brocchini et al.
patent: 5879697 (1999-03-01), Ding et al.
patent: 5879713 (1999-03-01), Roth et al.
patent: 5902875 (1999-05-01), Roby et al.
patent: 5905168 (1999-05-01), Dos Santos et al.
patent: 5910564 (1999-06-01), Gruning et al.
patent: 5914182 (1999-06-01), Drumheller
patent: 5914387 (1999-06-01), Roby et al.
patent: 5919893 (1999-07-01), Roby et al.
patent: 5925720 (1999-07-01), Kataoka et al.
patent: 5932299 (1999-08-01), Katoot
patent: 5955016 (1999-09-01), Goldfarb
patent: 5955509 (1999-09-01), Webber et al.
patent: 5955588 (1999-09-01), Tsang et al.
patent: 5958385 (1999-09-01), Tondeur et al.
patent: 5958638 (1999-09-01), Katayama et al.
patent: 5962138 (1999-10-01), Kolluri et al.
patent: 5968070 (1999-10-01), Bley et al.
patent: 5971954 (1999-10-01), Conway et al.
patent: 5980928 (1999-11-01), Terry
patent: 5980972 (1999-11-01), Ding
patent: 5993489 (1999-11-01), Lewis et al.
patent: 5993890 (1999-11-01), Marchant et al.
patent: 5997517 (1999-12-01), Whitbourne
patent: 6010530 (2000-01-01), Goicoechea
patent: 6011125 (2000-01-01), Lohmeijer et al.
patent: 6015541 (2000-01-01), Greff et al.
patent: 6033582 (2000-03-01), Lee et al.
patent: 6034204 (2000-03-01), Mohr et al.
patent: 6042875 (2000-03-01), Ding et al.
patent: 6048484 (2000-04-01), House et al.
patent: 6051576 (2000-04-01), Ashton et al.
patent: 6051648 (2000-04-01), Rhee et al.
patent: 6054553 (2000-04-01), Groth et al.
patent: 6056993 (2000-05-01), Leidner et al.
patent: 6060451 (2000-05-01), DiMaio et al.
patent: 6060518 (2000-05-01), Kabanov et al.
patent: 6080488 (2000-06-01), Hostettler et al.
patent: 6090134 (2000-07-01), Tu et al.
patent: 6096027 (2000-08-01), Layne
patent: 6096070 (2000-08-01), Ragheb et al.
patent: 6099562 (2000-08-01), Ding et al.
patent: 6110188 (2000-08-01), Narciso, Jr.
patent: 6110483 (2000-08-01), Whitbourne et al.
patent: 6113629 (2000-09-01), Ken
patent: 6120491 (2000-09-01), Kohn et al.
patent: 6120536 (2000-09-01), Ding et al.
patent: 6120788 (2000-09-01), Barrows
patent: 6120904 (2000-09-01), Hostettler et al.
patent: 6121027 (2000-09-01), Clapper et al.
patent: 6129761 (2000-10-01), Hubbell
patent: 6136333 (2000-10-01), Cohn et al.
patent: 6143354 (2000-11-01), Koulik et al.
patent: 6153252 (2000-11-01), Hossainy et al.
patent: 6159978 (2000-12-01), Myers et al.
patent: 6165212 (2000-12-01), Dereume et al
Lundkvist André-Jean
Roorda Wouter E.
Shah Niraj
Advanced Cardiovascular Systems Inc.
Meeks Timothy H
Sellman Cachet I
Squire Sanders & Dempsey L.L.P.
LandOfFree
Hemocompatible polymers on hydrophobic porous polymers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hemocompatible polymers on hydrophobic porous polymers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hemocompatible polymers on hydrophobic porous polymers will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4204060