Hemo dialyzer employing two dialysate solutions

Liquid purification or separation – With alarm – indicator – register – recorder – signal or... – Responsive to fluid flow

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Details

210321A, 210 22C, 210321B, B01D 3100, B01D 1300

Patent

active

039620751

ABSTRACT:
A novel dialysis system is disclosed for both making and using a hemo dialyzer employing two novel dialysate solutions. The dialyzer per se used in the system comprises a clamp assembly enclosing three parallel plate dialyzer boards. Between each pair of boards a pair of semipermeable filtration media is enclosed. A total of six chambers is formed, three between each pair of dialyzer boards. The two chambers bounded by the semi-permeable filtration media form a portion of the flow path for the liquid to be dialyzed, in this case, blood. Of the remaining four chambers, two form a portion of a flow path of one dialysate solution and the other two chambers form a portion of the flow path for the remaining dialysate solution. Suitable connections are made on each of the boards for the introduction and withdrawal of the two dialysate solutions and suitable ports are provided to communicate with the membrane formed chambers for the introduction and withdrawal of the liquid to be dialyzed.
The two novel dialysate solutions are similar in that neither contain any concentration of urea. However, one of the dialysate solutions is hypertonic, that is, it contains a greater concentration of other constituents to be dialyzed than does the liquid to be dialyzed. The other dialysate solution is hypotonic with respect to the other constituents to be dialyzed, that is, it contains a lower concentration of these constituents than does the liquid to be dialyzed.
The rate of dialysis is greatly increased by the use of two different dialysate solutions as compared with the prior art processes which employ one dialysate solution. This greatly-increased dialysis rate enables the use of the parallel plate dialyzer, the use of which had substantially been discontinued.

REFERENCES:
patent: 3212498 (1965-10-01), McKirdy et al.
patent: 3352779 (1967-11-01), Austin et al.
patent: 3412865 (1968-11-01), Lontz et al.
patent: 3525686 (1970-08-01), Roberts
patent: 3727612 (1973-04-01), Sayers et al.
patent: 3757947 (1973-09-01), Wakefield et al.

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