Hemihydrate of a selective functional M1 muscarine receptor...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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C564S161000

Reexamination Certificate

active

10524960

ABSTRACT:
The present invention provides crystalline biphenyl-4-carboxylic acid (R)-(6-(1-((4-fluorobenzyl)methylamino)ethylideneamino)-2(R)-hydroxyindan-1-yl)amide hemihydrate, compositions thereof, methods of using the same, processes for making the same, and processes for making intermediates thereof.

REFERENCES:
patent: 2004/0242584 (2004-12-01), Allen et al.
patent: WO 03/027061 (2003-04-01), None
Shannon et al. “Xanomeline, an M1/M4 preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice” Schizophrenia Research 2000, vol. 42, pp. 249-259.

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