Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1994-03-31
1996-03-26
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424465, 424489, A61K 916, A61K 920
Patent
active
055018602
DESCRIPTION:
BRIEF SUMMARY
TECHNICAL FIELD
The present invention relates to a binder and a product using the same. More particularly, it is concerned with a binder comprising as an active ingredient a water-soluble hemicellulose derived from beans, a sugar coating composition comprising said binder, a sugar coated composition comprising a composition coated with said sugar coating composition, granules of powder prepared in the production of lemonade-flavored confectionery and tablets containing said binder and tableted products provided by tableting the granules.
In the present invention, the term "sugar coat" is intended to mean a sweet coating containing sugar, which coating is applied to confectionery and tablets. The term "sugar coating composition" is intended to mean a composition for the production of the sugar coating. The term "sugar coated composition" is intended to mean a composition having a sugar coating such as sugar coated confectionery or tablets.
BACKGROUND ART
In sugar coated confectionery, such as marble chocolates, and sugar coated tablets, such as pharmaceuticals, a coating of a saccharide, such as sugar, is formed on the surface of a material to protect the material or render the material easy to eat or swallow. The sugar coating is usually effected as follows. An aqueous sugar solution is mixed with an assistant comprising a polysaccharide, such as gum arabic, chemically modified starch or dextrin, or a protein, such as gelatin, to prepare a sugar solution having high viscosity and concentration. This sugar solution is put on a material to be coated in a rotary kiln and subjected to forced draft drying. This procedure is repeated several times to form a coating.
On the other hand, tableted confectionery, such as lemonade-flavored confectionery, and tablets, such as pharmaceuticals, are produced by kneading various powdery raw materials as main ingredients with a solution of a binder, such as gum arabic, or granulating the main ingredients, effecting compression molding, such as tableting, and optionally drying the tablets. In the tableted confectionery and tablets prepared without use of any binder, partial breaking or cracking occurs due to physical force applied internally or externally during production or storage after the production. On the other hand, when a binder is used and granules of powder are prepared prior to tableting, use of the binder is indispensable because if good granules having a homogeneous size cannot be prepared, the subsequent workability would become poor. The gum arabic used as the binder is obtained by refining exudates of trees belonging to the genus Acacia.
In recent years, however, the production of the gum arabic has been sharply decreased due to abnormal weather and a change of government in the Sudan, a main gum arabic producing country. This has resulted in an increase in price of the gum arabic and produced sharp fluctuations in the production and price of the gum arabic. Binders, which are stable in price, include gelatin and dextrin. However, the binding force thereof is so low that, during the sugar coating operation, cracking occurs on the surface of the sugar coating or sugar coating comes off. Further, good granules as described above cannot be prepared using gum arabic and polysaccharides such as dextrin. For this reason, sugar coating compositions, which can provide a high coating strength, can be stably supplied and are inexpensive, and binders for granules and tableted products, which have a high binding force, enable good granules to be prepared before tableting, are naturally occurring, have a low price and can be produced stably, have been desired in the art.
DISCLOSURE OF THE INVENTION
An object of the present invention is to provide a binder which, in coating of sugar on confectionery or tablets, exhibits a workability, a coat forming property and a sugar coating strength equivalent or superior to assistants such as gum arabic, which can be stably supplied and is inexpensive, and a sugar coating composition, a granulated product and a tableted produc
REFERENCES:
patent: 4927649 (1990-05-01), Antenucci
patent: 5151273 (1992-09-01), Korsatko-Wabnegg et al.
Furuta Hitoshi
Maeda Hirokazu
Shimizu Hiroshi
Takahashi Taro
Fuji Oil Co., Ltd.
Page Thurman K.
Spear James M.
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