Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1996-05-23
1998-08-11
Eisenschenk, Frank C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 695, 435335, C07H 2104, C12N 1500, C12P 2102
Patent
active
057928509
ABSTRACT:
Novel receptor polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides comprise an extracellular ligand-binding domain of a cell-surface receptor that is expressed at high levels in lymphoid tissue, including B-cells and T-cells. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo.
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Baumgartner James W.
Foster Donald C.
Grant Frank J.
Sprecher Cindy A.
Eisenschenk Frank C.
Nolan Patrick
Parker Gary E.
ZymoGenetics Inc.
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