Hemagglutination-inhibition test for togaviruses

Details Hemagglutination-inhibition test for togaviruses Hemagglutination-inhibition test for togaviruses

1976-11-08

1979-02-20

Fagelson, Anna P.

Drug, bio-affecting and body treating compositions

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23230B, 195 14, 195 63, 195 69, 1951035V, 424 8, 424 86, 424 89, G01N 3100, G01N 3316

Patent

active

041407547

ABSTRACT:
The non-specific inhibitors of hemagglutination in a subject serum for hemagglutination-inhibition test for a togavirus such as rubella virus can be inactivated by subjecting the subject serum to the action of phospholipase C. By subjecting thus-treated serum to the hemagglutination-inhibition test employing fixed erythrocytes the togavirus hemagglutination-inhibition antibody titer of the serum can be determined accurately and with high sensitivity.

REFERENCES:
Nakagawa, Chem. Abs., vol. 52, 1958, p. 20389ghi.
Schmidt, Chem. Abs., vol. 75, 1971, Ab. No. 33041r.
Plotkin, Amer. J. of Epidemiology, vol. 88, Nov. 1968, pp. 301-304.
Gupta, Applied Microbiol., vol. 22, 1971, pp. 921-922.
Haukenes, Med. Microbiol. Immunol., vol. 161, No. 2, 1975, pp. 99-106.

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