Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Patent
1995-06-07
2000-07-25
Guzo, David
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
435455, 435456, 4353201, 435325, 435366, 435367, 435369, C12N 1563, C12N 1564, C12N 510, C12N 15864
Patent
active
060935707
ABSTRACT:
A method for the production of adeno-associated virus stocks and recombinant adeno-associated virus stocks that are substantially free of contaminating helper virus is described. The method utilizes transfection with helper virus vectors to replace the infection with helper virus used in the conventional method.
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Ferrari Forrest K.
Samulski Richard Jude
Xiao Xiao
Guzo David
The University of North Carolina at Chapel Hill
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