Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-09-13
2005-09-13
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S271000
Reexamination Certificate
active
06943167
ABSTRACT:
Compounds which mimic the secondary structure of helical regions of biologically active peptides and proteins having the following structure:including pharmaceutically acceptable salts and stereoisomers thereof, wherein Y, A, B, R1and R2are as defined herein. Such compounds have utility over a wide range of applications, including use as diagnostic and therapeutic agents. In particular, compounds of this invention, and pharmaceutical compositions containing the same, are neurokinin (tachykinin) antagonists. Libaries contaning the compounds of this invention are also disclosed, as well as methods for screening such libaries identify biologically active members.
REFERENCES:
patent: 5446128 (1995-08-01), Kahn
patent: 5710245 (1998-01-01), Kahn
patent: 5840833 (1998-11-01), Kahn
patent: 5859184 (1999-01-01), Kahn et al.
patent: 1130022 (2001-09-01), None
Eguchi Masakatsu
Huber Vincent
Lee Min Sang
Mathew Jessymol
Nakanishi Hiroshi
Kifle Bruck
Lev, III Herbert L.
Myriad Genetics Inc.
Myriad IP Department
Zhang Jay Z.
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