Heliothis subflexa cell line for the production of baculoviruses

Details Heliothis subflexa cell line for the production of baculoviruses Heliothis subflexa cell line for the production of baculoviruses

1993-01-21

1995-04-11

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

435236, 435239, 4352402, 43524021, 43524025, C12N 704, C12N 708, C12N 502

Patent

active

054057701

ABSTRACT:
A cell line obtained from Heliothis subflexa, designated BCIRL-HS-AM1, and an in vitro process using the cell line to produce viral agents including viruses, viral particles, and/or occlusion bodies. The cell line is particularly useful in the production of baculoviruses and occlusion bodies of baculoviruses.

REFERENCES:
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patent: 4911913 (1990-08-01), Hostetter et al.
patent: 5024947 (1991-06-01), Inlow et al.
patent: 5041379 (1991-08-01), Fraser et al.
patent: 5169784 (1992-12-01), Summers et al.
McIntosh, Arthur H., et al., "Replication of Autographa Californica Nuclear Polyhedrosis Virus in Five Lepidopteran Cell Lines", Journal of Invertebrate Pathology, 54, pp. 97-102, 1989.
McIntosh, Arthur H., "In Vitro Infectivity of a Clonal Isolate of Syngrapha falcifera (Celery Looper) Multiple Nuclear Polyhedrosis Virus", Journal of Invertebrate Pathology, 57, pp. 441-442, 1991.

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