Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Reexamination Certificate
2007-09-18
2007-09-18
Graser, Jennifer E. (Department: 1645)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
C435S006120, C435S091100, C435S091210, C536S023700, C536S024300, C536S024320, C536S024330, C204S166000
Reexamination Certificate
active
10922263
ABSTRACT:
The present invention provides methods for detectingHelicobacter pylori(H. pylori) DNA and/or fragments thereof in blood. The first method involves extracting DNA from a blood sample, preferably plasma, by amplifying the DNA using a polymerase chain reaction (PCR) or a ligase chain reaction (LCR) method, and detecting a target DNA sequence in the amplified DNA. The preferred target DNA sequence comprises a Mr26 or a 16S rRNA gene or fragments thereof specific toH. pylori. The second method involves extracting DNA from a blood sample, preferably serum, by hybridizing the extracted DNA with a radioisotope or fluorescence labeledH. pyloriDNA probe.
REFERENCES:
patent: 5527678 (1996-06-01), Blaser et al.
patent: 5716791 (1998-02-01), Larka et al.
patent: 5871942 (1999-02-01), Larka et al.
patent: 5932430 (1999-08-01), Larka et al.
patent: 6153390 (2000-11-01), Cover et al.
patent: 6245516 (2001-06-01), Al Rashid et al.
patent: 0 329 570 (1989-08-01), None
patent: 0 806 667 (1997-11-01), None
patent: WO99/41611 (1999-08-01), None
patent: WO 00/29432 (2000-05-01), None
Lu et al (J.Clin.Microbiol., Mar. 199. 37(3): 772-774).
Blasi et al (JID. Dec. 1, 1999. 180: 2074-2076).
Marshall, Barry;Helicobacter pylori—The Etiologic Agent for Peptic Ulcer; JAMA, Oct. 4, 1995, vol. 274, No. 13, p. 1064-1066.
Howden, Colin; Testing forH. pyloriin the Post-treatment Period; The American Journal of Medicine, May 20, 1996, vol. 100 (suppl 5A), p. 5A-39S-5A-41S.
Cutler, Alan; Testing forHelicobacter pyloriin Clinical Practice; The American Journal of Medicine, May 20, 1996, vol. 100 (suppl 5A), p. 5A-35-5A-38S).
Jang-Jih Lu et al.; Comparison of five PCR method for detection ofHelicobacter pyloriDNA In gastric tissues; Journal of Clinical Microbiology, vol. 37, No. 3, Mar. 1999, pp. 772-774.
Genta, Robert; Simultaneous Visualization ofHelicobacter pyloriGastric Morphology: a New Stain; Human Pathology, Mar. 1994, vol. 25, No. 3, p. 221-226.
Han. S.W.: Transport and Storage ofHelicobacter pylorifrom Gastric Mucosal Biopsies and Clinical Isolates; Eur. J. Clin. Microbiol. Infect. Dis., vol. 14, 1995, p. 349-352.
Tomb, J.F. et al., Nature, vol. 388, pp. 539-547.
Danesh, J., et al., The Lancet, vol. 350 (9075), pp. 430-436 (abstract).
Hsueh, P.R., et al., Journal of Clinical Microbiology, vol. 37(6), pp. 2084-2086 (abstract).
Hung, C.C., et al., Journal of Formosan Medical Association, vol. 96(7), pp. 558-560, (abstract).
Husmann, M., et al., Journal of Clinical Microbiology, vol. 32(12), pp. 3037-3039.
Kemper, C.A., et al., Journal of Infection, vol. 26(1), pp. 97-101.
Lastovica, A.J., et al., Abstracts of the General Meetingof the American Society of Microbiology, vol. 97(0), pp. 168, May 4-8 (abstract).
Ndawula, E.M., et al., European Journal of Clinical Microbiology and Infectious Diseases, vol. 13(7), p. 621, July (abstract).
Negrini, R., et al., Gastroenterology, Sep. 1996, vol. 111(3), pp. 655-665, (abstract).
Kiehlbauch, J.A., et al., Annals of Internal Medicine, vol. 121(2) pp. 90-93, Jul. 15, (abstract).
Orticek, S.L., et al., Journal of Clinical Microbiology, vol. 31(3), pp. 569-571, Mar. 1993 (abstract).
Tee, W., et al., Scandinavian Journal of Infectious Diseases, vol. 28(2), pp. 199-203, (abstract).
Trivett-Moore, N.L., et al., Journal of Clinical Microbiology, vol. 35(5), pp. 1144-1150, May 1997 (abstract).
O'Toole, P.W., Isolation and Biochemical and Molecular Analysis of a Species-Specific Protein Antigen from the Gastric PathogenHelicobacter pylori, vol. 173, No. 2, pp. 505-513, Jan. 1991.
Andrews Kruth LLP
Chao Fei-Fei
Graser Jennifer E.
Joy Biomedical Corporation
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