Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Reexamination Certificate
2005-08-23
2005-08-23
Moran, Marjorie (Department: 1631)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
C530S395000
Reexamination Certificate
active
06933142
ABSTRACT:
Mammalian glycosylsulfotransferases expressed in high endothelial cells (HEC-GLCNAC6ST) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith, particularly by administering an inhibitor of at least one of HEC-GLCNAC6ST or KSGal6ST, or homologues thereof.
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Bistrup Annette
Hemmerich Stefan
Rosen Steven D.
Borden Paula A.
Bozicevic Field & Francis LLP
Moran Marjorie
Syntex (USA) LLC
The Regents of the University of California
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