Heavy metal salts of hyaluronic acid and their use as antimicrob

Details Heavy metal salts of hyaluronic acid and their use as antimicrob Heavy metal salts of hyaluronic acid and their use as antimicrob

1986-03-14

1988-05-24

Richman, Barry S.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 78, 424DIG13, 424 28, 424 95, 424 81, 536 41, 524 27, 524 29, 525 542, 604890, 514 54, 514914, 514825, A61K 4300, A01N 6302, A01N 5502, A01N 31295

Patent

active

047465042

ABSTRACT:
Heavy metal salts of hyaluronic acid have been prepared. In particular, this invention is directed to silver, gold, cerium and tungsten salts of hyaluronic acid. These heavy metal salts of hyaluronic acid are useful as antimicrobial agents. Gold hyaluronate may also be used to treat arthritis. This invention also concerns methods of making the silver salt of hyaluronic acid as well as compositions containing silver hyaluronate or gold hyaluronate. The invention also concerns composition containing heavy metal salts having radioactively labelled hyaluronate moieties.

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O. Schmut and H. Hofmann, "Preparation of Gels from Hyaluronate Solutions", Graefe's Arch Clin Exp Ophthalmol 218: 311-314, (1982).
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