Heat sterilization of cyanoacrylate

Details Heat sterilization of cyanoacrylate Heat sterilization of cyanoacrylate

1998-01-30

2000-10-24

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

424443, 424 7803, A61K 600, A61K 700, B01J 1900

Patent

active

06136326&

ABSTRACT:
Cyanoacrylate preparations for medical and surgical applications are sterilized by heating in a suitable container at a temperature of at least 160.degree. C. The preferred container is a squeezable aluminum tube and the preferred temperature is above 170.degree. C. Cyanoacrylate adhesive compositions sterilized by heat have improved shelf life compared to those sterilized by ionizing radiation.

REFERENCES:
patent: 2912454 (1959-11-01), McKeever et al.
patent: 3527841 (1970-09-01), Wicker, Jr. et al.
patent: 4724177 (1988-02-01), Russo
patent: 5436363 (1995-07-01), Wang et al.
patent: 5530037 (1996-06-01), McDonnell et al.
patent: 5649648 (1997-07-01), Lier er al.

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