Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...
Patent
1980-08-27
1982-09-14
Naff, David M.
Chemistry: molecular biology and microbiology
Carrier-bound or immobilized enzyme or microbial cell;...
Enzyme or microbial cell is immobilized on or in an organic...
435215, 435188, C12N 972, C12N 1108, C12N 996
Patent
active
043496300
ABSTRACT:
A heat-resistant water soluble derivative of urokinase is prepared which comprises urokinase covalently bonded to a copolymer of acrylamide and acrylic acid having a molecular weight of 10,000 to 200,000 and a content of acrylic acid of 1% to 2%. The derivative contains 15% to 35% urokinase and has an esterase and amidolytic activity of from 10% to 80%.
REFERENCES:
patent: 3625827 (1971-12-01), Wildi et al.
patent: 3876501 (1975-04-01), Hanushewsky
patent: 4106992 (1978-08-01), Vairel et al.
Chazov Evgeny I.
Maximenko Alexandr V.
Smirnov Vladimir N.
Torchilin Vladimir P.
McCowin Kathleen
Naff David M.
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